Nombor Cas Acarbose: 56180-94-0 Formula Molekul：C25H43NO18
Precos
Precose
Prandase
ACARBOSE
Glucobay
bay-g5421
Ascarbose
API Acarbose
Acarbose ,98%
Acarbose Hydrate
Teluk g 5421：Glucobay
Acarbose (Acarbosum)
4)-OaD-glucopyranosyl-(1®
-alpha-d-glucopyranosyl-(1-4)-
AMylostatin J, Bay g 5421, alpha-GHI
(2R,3R,4R,5S,6R)-5-((2R,3R,4R,5S,6R)-5-
Acarbose fom Actinoplanes sp.ca.100 FIP-AIU/mg
O-4,6-DIDEOXY-4-[[[1S-(1A,4A,5BETA,6A)]-4,5,6-TRIHYDROXY-3-(HYDROXYMETHY
d-glukosa,o-4,6-dideoxy-4-(((1s-(1-alpha,4-alpha,5-beta,6-alpha))-4,5,6-trihyd
roxy-3-(hydroxymethyl)-2-cyclohexen-1-yl)amino)-alpha-d-glucopyranosyl-(1-4)-o
4",6"-Dideoxy-4"-([1S]-[1,4,6/5]-4,5,6-trihydroxy-3-hydroxymethyl-2-yclohexenylamino)-maltotriose
D-Glucose,O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino] -aD-glucopyranosyl-(1®
O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D -glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-Glukosa
4-O-[4-O-[4-[[(1S,4R,5S,6S))-4,5,6-Trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-4 ,6-dideoxy-α-D-glucopyranosyl]-α-D-glucopyranosyl]-D-glucopyranose
D-Glucose, O-4,6-dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino] -α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranosyl-(1→4)-
O-4,6-Dideoxy-4-[[[1S-(1a,4a,5,6a)]-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino] -aD-glucopyranosyl-(1-4)-OaD-glucopyranosyl-(1-4)-D-glukosa
O-4，6-Dideoxy-4-[[[1S(1α，4α，5β，6α-)-)-4，5，6-trihydrDxy-3-(hydroxymethyl)-2-cyclohexen-1-y1]amino]- α-D-glucopyranosyl-(1→4)-O-α-D-ducopyranosyl-(1→4)-D-glukosa
O-4,6-Dideoxy-4-[[[1S-(1α,4α,5β,6α)]-4,5,6-trihydroxy-3-(hydroxyMethyl)-2-cyclohexen-1-yl]aMino] -α-D-glucopyranosyl-(1-4)-O-α-D-glucopyranosyl-(1-4)-D-glukosa
O-4,6-Dideoxy-4-[[[1S-(1a,4a,5b,6a)]-4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino] -aD-glucopyranosyl-(1-4)-OaD-glucopyranosyl-(1-4)-D-gluco-
se
D-Glucose, O-4,6-dideoxy-4-[[4,5,6-trihydroxy-3-(hydroxymethyl)-2-cyclohexen-1-yl]amino]-α-D-glucopyranosyl-(1→ 4)-O-α-D-glucopyranosyl-(1→4)-, [1S-(1α,4α,5β,6α)]-
O-4,6-DIDEOXY-4-[[[1S-(1A,4A,5BETA,6A)]-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-2-CYCLOHEXEN-1-YL]AMINO] -ALPHA-D-GLUCOPYRANOSYL-(1-4)-O-ALPHA-D-GLUCOPYRANOSYL-(1-4)-D-GLUCOSE
5-[5-[3,4-DIHYDROXY-6-METHYL-5-[[4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-1-CYCLOHEX-2-ENYL]AMINO]OXAN-2-YL] OXY-3,4-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY-6-(HYDROXYMETHYL)OXANE-2,3,4-TRIOL
| Takat lebur | 165-170°C |
| Ketumpatan | 1.4278 (anggaran kasar) |
| suhu penyimpanan | Suasana lengai, Suhu Bilik 2-8°C |
| keterlarutan | Sangat larut dalam air, larut dalam metanol, boleh dikatakan tidak larut dalam metilena klorida. |
| aktiviti optik | T/A |
| Penampilan | Pepejal Putih-Putih |
| Kesucian | ≥97% |
Acarbose, oligosakarida kompleks yang diasingkan daripada Actinoplanes, dilaporkan berguna sebagai terapi pembantu dalam diabetes.Dengan menghalang alpha-glucosidase, acarbose melambatkan metabolisme karbohidrat dalam saluran gastrousus dan memodulasi perubahan dalam paras gula darah yang disebabkan oleh makanan.
Acarbose ialah pseudo-oligosakarida dengan terminal C7-cyclitol yang dipatenkan pada tahun 1975 oleh Bayer.Acarbose ialah komponen kompleks amilostatin yang dihasilkan oleh spesies Actinoplanes dan Streptomyces.Acarbose bertindak sebagai perencat kuat α-glukosidase dan sakarase.Sejak tahun 1990, acarbose telah digunakan secara terapeutik untuk rawatan diabetes jenis 2.
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